Chemical structure properties

Predict

Apply predictive models

Data sources

REACH Study Results 25245 / 2266496
OpenFoodTox 5256 / 19574
REPDOSE - RELATIONAL DATABASE ON SUBACUTE TO CHRONIC TOXICITY 194 / 3081

Legal notice

The LRI AMBIT - IUCLID tool is loaded with non-confidential REACH data supplied by ECHA. The legal notice from the ECHA dissemination website applies to the AMBIT users. In addition, Cefic disclaims any liability of whatsoever nature either direct or indirect regarding the use of the AMBIT-IUCLID tool or information / data contained in it. IdeaConsult is a contractor of Cefic developing and hosting the AMBIT-IUCLID tool. Some data used may have been provided by Cefic. IdeaConsult has acted solely on the instructions of Cefic. IdeaConsult disclaims any liability of whatsoever nature, direct or indirect, regarding the use of any information/data by the AMBIT-IUCLID tool. IdeaConsult shall not have any liability of whatsoever nature for any use or misuse of the AMBIT-IUCLID tool.

AMBIT supports read across and category formation of chemicals, which are indispensable techniques in the safety assessments of chemicals. Comprehensive assessment workflows are developed for read-across and category formation based on all the data available in AMBIT. The assessment workflow facilitates the search for target and source structures, generating data matrices, gap filling and generating assessment reports with predefined formats automatically.

ToxTree models

all modules (3.1.0)

VEGA models

Mutagenicity (Ames test) model (CAESAR) (2.1.14)
Estrogen Receptor-mediated effect (IRFMN-CERAPP) (1.0.1)
Estrogen Receptor Relative Binding Affinity model (IRFMN) (1.0.2)
Thyroid Receptor Beta effect (NRMEA) (1.0.1)
Ready Biodegradability model (IRFMN) (1.0.10)
Total body elimination half-life (QSARINS) (1.0.1)
Fathead Minnow LC50 96h (EPA) (1.0.10)
Adipose tissue - blood model (INERIS) (1.0.1)
Developmental Toxicity model (CAESAR) (2.1.8)
Skin Permeation (LogKp) model (Ten Berge) (1.0.1)
Androgen Receptor-mediated effect (IRFMN-COMPARA) (1.0.1)
Skin Permeation (LogKp) model (Potts and Guy) (1.0.1)
BCF model (CAESAR) (2.1.15)
Mutagenicity (Ames test) model (SarPy-IRFMN) (1.0.8)
Thyroid Receptor Alpha effect (NRMEA) (1.0.1)
Carcinogenicity model (CAESAR) (2.1.10)
Hepatotoxicity model (IRFMN) (1.0.1)
Daphnia Magna LC50 48h (EPA) (1.0.9)
In vitro Micronucleus activity (IRFMN-VERMEER) (1.0.1)
Skin Sensitization model (CAESAR) (2.1.7)
All 78 modules ()